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  • Alexander Saibedinov

    Governor Svetliy lyceum principal, the Russian Federation national teacher, a member of Tomsk region Public Chamber.

  • Vladimir Knyaginin

    Director of the Center for Strategic Research “North-West”

  • Vladimir Artisyuk

    Vice-Rector for Research and International Affairs, Central Institute of Advanced Training (Atomenergoprom, Russia)

  • Cynthia Bouthot

    Founding Partner of the Russia Innovation Collaborative

  • Dmitry Bakhturin

    A coordination board member, International network of specialists for nuclear and radiation hazardous objects decommissioning (IAEA)

  • Martha Russell and Neil Rubens

    ”MediaX” research group, Stanford University

  • Sergey Galibeev

    Director general of NIOST, LLC

  • Nikolay Protsenko

    Deputy chief editor of “Expert South”, co-founder of the non-profit partnership “Project: Innovations in Humanities”

  • Yuri Dekhtyar and Igor Khlusov

    Yuri Dekhtyar, professor, director of Institute of biomedical engineering and nanotechnologies of Riga technical university, president of Latvian medical-engineering and physical society, member of New-York academy of science, expert of medical physical and engineering European network, member of European physical society. Igor Khlusov, leader of educational and research center “Biocompatible materials and bioengineering” of Siberian state medical university, professor of the department of morphology and general pathology of Siberian state medical university, Doctor of medical science.

  • Denis Molotkov

    Tomsk city Mayor Deputy for investments

  • Boris Elkonin

    Head of laboratory “Theoretical and Experimental Problems of Developmental Psychology”, Psychological Institute of the Russian Academy of Education, Vice-President of the International Association of Developmental Education, PhD in Psychology, full professor, Moscow

  • Lyudmila Ogorodova

    Vice-Rector for Research and Postgraduate Internship (Siberian State Medical University), Head of Technology Platform “Medicine of the Future”

  • Denis Molotkov

    Tomsk city Deputy Mayor

  • Viktor Gyunter

    CEO of Micran, reseacrh & production company, CJSC

  • Sergey Ketov

    Professor of the Tokyo Metropolitan University

  • Synthia Bouthot, Daniel Satinsky and Chris King

    Partners in Russia Innovation Collaborative

  • Jury Maksimenko

    Chairman deputy of the Russian Union of Industrialists and Entrepreneurs Committee on environmental, industrial and technological security, leader of the project “Service of ecology and industrial risks”, The Company “Basic element” – speaker of Environmental standards is the engine of innovative economy round table

  • Thomas Werner

    Professor of “Parsons The new school for design”

  • Sergey Gradirovskiy

    Expert in regional urban development, President of the Public Council of the Ministry of Health and Social Development

  • Sergey Poglyad

    Associate director for strategy and development of Scientific Research Institute of Atomic Reactors

  • Vladimir Dovgiy

    Deputy Director General of Inter-institutional analytical center

  • Ilya Savchuk

    Metaver group Director for development programs, co-developer of Education 2030 foresight

  • Alexandr Uvarov

    TUSUR Vice-Rector for Innovations and international development, Institute of Innovations Director, Head of Russian branch of Triple helix association

  • Marat Kapelyushnik

    Astelion company founder and Director General, an expert in the field of high-tech and innovative business management.

  • Valeriy Kagadey

    General Director Deputy of Micran, Research and Production Company, Doctor of Physical and Mathematical Sciences

Yuriy Lishmanov and Nikolay Krivonogov

Yuriy Lishmanov, Head of Radionuclide Research Methods Laboratory of Cardiology Research Institute, SB RAS, associate member of RAMS, M.D., professor. Nikolay Krivonogov, M.D., professor, senior research assistant of Radionuclide Research Methods Laboratory of Cardiology Research Institute, SB RAS.

An interview about radio technologies future, diagnostics breakthrough and nuclear medicine center foundation for service rendering on the basis of advanced technologies.

Implementation of nuclear technologies in medicine has become a separate branch called nuclear medicine. What are the main functioning principles and specific features of this sphere today?

Yuriy Lishmanov, Head of Radionuclide Research Methods Laboratory of Cardiology Research Institute, SB RAS, associate member of RAMS, M.D., professorYu. Lishmanov: Nuclear medicine is a part of radiation medicine, radiodiagnostics and radiotherapeutics, connected with the usage of diagnostic and therapeutic radioisotopes. Short-living isotopes or radionuclides emitting gamma-rays are diagnostic ones. There are long-living isotopes. Isotopes, put in the organism, let us register emission from the place of their gathering and estimate the processes taking place.

N. Krivonogov: X-ray radiation is an external one in relation to an organism. In nuclear medicine rays are emitted from inside the organ, which has accumulated a certain irradiating radionuclide, an isotope. Then we register such radiation and obtain basis for precise diagnosis.

Can nuclear medicine be considered as a breakthrough in diagnostics?

Yu. Lishmanov: Nuclear medicine and x-ray radiation are the parts of radiodiagnosis, thanks to which 90% of correct diagnosis are made statistically. Radiopharmaceutical (pharmaceutical, marked with radionuclide) is put in the organism. Thus the isotope connected to pharmaceutical is cumulated in heart and allows determining its condition.

N. Krivonogov: Radiopharmaceutical is cumulated selectively by different organs or organ systems.

Yu. Lishmanov: About 80% of patients with malignant tumors are successfully treated with the help of beta-ray therapy use which also includes radionuclide therapy with radioactive sources application.

N.Krivonogov: Nuclear medicine uniqueness is in running diagnostics of organ or organ system at the early stage of desease, detect defects at molecular and cellular levels when the other diagnostics methods define the organ condition as normal. In this situation rentgenologic and magnetic resonance imaging procedures does not allow making correct diagnosis.

What contribution can be made by the nuclear medicine to treatment modalities and therapy?

Yu. Lishmanov: Curative and therapeutic nuclear medicine is connected with radioactive isotopes usage for medicinal purposes. Non-penetrating beta-emitters and gamma-emitters (for instance Strontium 89) are applied. They are accumulated in bones and attacks malignant cells if there are metastasize, giving minimal irradiation to the organism on the whole.

How does radiation medicine develop globally today and what are the obstacles for its development in Russia?

Nikolay Krivonogov, M.D., professor, senior research assistant of Radionuclide Research Methods Laboratory of Cardiology Research Institute, SB RASYu. Lishmanov: World radiopharmaceutical market grows by 10−15% annually. More than 50% of world’s radio nuclides yearly output are spent for nuclear medicine needs. More than 13 million of people in the USA are medically examined using nuclear medicine methods.

There are problems connected with radio nuclides production in Russia due to different reasons. There is no production of technetium generator, which is one of the main isotopes included in many pharmaceuticals. There are also such radiopharmaceuticals which are neither imported nor produced in Russia, and those reactors, which produced them previously, are either under maintenance or closed up. Radioactive molybdenum, raw material for technetium production, price has surged dramatically. However, technology of the most actual radionuclide production has been already assimilated. Tomsk Institute of Nuclear Physics developed its ecologically harmless technology of technetium production through reactor irradiation without the use of radioactive molybdenum.

N. Krivonogov: Tomsk is a unique city. Besides technetium producing reactor, cyclotron is utilized for making radiopharmaceuticals applied in diagnostics, such as iodine-123 widely used in radionuclide diagnostics.

Describe the future of nuclear medicine. What prospective lines of nuclear medicine development can you single out?

N. Krivonogov: Radiology will become one of Tomsk atomic cluster priorities. It is connected with three directions, first of which is the development of ultra short-living radiopharmaceuticals. The second one is foundation of Tomsk nuclear medicine center with equipment enabling registrating positron emitting radiopharmaceuticals. There are about 600−800 such centers in Europe and America in total and two canters are in the Russian Federation – in Saint-Petersburg and Moscow.

Yu. Lishmanov: 3 centers will be built during the next 5 years in Dimitrovgrad, Obninsk and Tomsk.

N. Krivonogov: The third direction, which should be developed, is nuclear therapy, radioiodinetherapy, for instance. It will give an opportunity to treat thyroidea malignant tumors. But it requires establishing of dispensary service.

Comments

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